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Different formulations of phentermine as a single agent are available under various brand names(Adipex-P, Phen375, Phentermine 37.5 mg etc.), in many countries.
Phentermine is used for a short period of time to promote weight loss if exercise and calorie reduction are not sufficient and in addition to exercise and calorie reduction. Phentermine is approved for up to 12 weeks of use and most weight loss occurs in the first weeks. However, significant loss continues through the sixth month and has been shown to continue at a slower rate through the ninth month.
Gastrointestinal effects include nausea, vomiting, dry mouth, cramps, unpleasant taste, diarrhea, and constipation.
Other adverse effects include trouble urinating, rash, impotence, changes in libido, and facial swelling. Cardiovascular effects like palpitations, tachycardia, high blood pressure, precordial pain; rare cases of stroke, angina, myocardial infarction, cardiac failure and cardiac arrest have been reported. Central Nervous System effects like overstimulation, restlessness, nervousness, insomnia, tremor, dizziness and headache; there are rare reports of euphoria followed by fatigue and depression, and very rarely, psychotic episodes and hallucinations.
Rare cases of pulmonary hypertension and cardiac valvular disease have been reported. Tolerance usually occurs however risks of dependence and addiction are considered negligible. People taking phentermine may be impaired when driving or operating machinery. Consumption of alcohol with phentermine may produce adverse effects.
There is no evidence that phentermine is safe for women who are pregnant.
History of Phentermine
In 1959, phentermine first received approval from the United States FDA as an appetite suppressing drug. Eventually, a hydrochloride salt and a resin form became available.
Phentermine was marketed with fenfluramine or dexfenfluramine as a combination appetite suppressant and fat burning agent under the popular name fen-phen. In 1997, after 24 cases of heart valve disease in fen-phen users, fenfluramine and dexfenfluramine were voluntarily taken off the market at the request of the FDA. Studies later showed nearly 30% of people taking fenfluramine or dexfenfluramine for up to 24 months had abnormal valve findings.
Phentermine is still available by itself in most countries, including the US. However, because it is similar to amphetamine, it is classified as a controlled substance in many countries. Internationally, phentermine is a schedule IV drug under the Convention on Psychotropic Substances. In the United States, it is classified as a Schedule IV controlled substance under the Controlled Substances Act. In contrast, amphetamine preparations are classified as Schedule II controlled substances.
A company called Vivus developed a combination drug, phentermine/topiramate that it originally called Qnexa and then called Qsymia, which was invented and used off-label by Thomas Najarian, who opened a weight clinic in Los Osos, California in 2001; Najarian had previously worked at Interneuron Pharmaceuticals, which had developed one of the fen-phen drugs previously withdrawn from the market. The FDA rejected the combination drug in 2010 due to concerns over its safety. In 2012 the FDA approved it after Vivus re-applied with further safety data. At the time, one obesity specialist estimated that around 70% of his colleagues were already prescribing the combination off-label.
Why Phentermine 37.5 mg buy online?
Phentermine aims at people who are extremely obese, in cases where their health could be at significant risk if they do not lose weight. Up until a year or so, it was the most commonly used slimming pills in the world being available both online and from most doctors.
Phentermine is designed to increase the body’s metabolic rate as well as help suppress appetite. The most common reason that dieting is so difficult is due to the inability to control appetite and maintain an optimal metabolic rate.
Skipping meals is not the best solution but controlling them is. Appetite control is essential to long-term weight loss. Skipping meals actually force your body to go into a starvation mode. It slows down the metabolic rate to preserve itself and makes the fat burning process more difficult. Ideally, you want to reduce calories, while also increasing meal frequency. Phentermine will aid you in controlling your appetite and along with your diet plans, the process becomes easier to accomplish.
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